The neurotransmitter that takes you high ;)

'highest' neurotransmitter'

Seretonin and dopamine are neuro-transmitters, DMT is the highest in the body'

It carries information through neurons in the brain'

9/10th the speed of light'

bliss'

Motumba'

Well, that could be since Harmine, Harmaline, Tetra-Hydro-Harmaline...ect. are all MAO-I... Which means they do act as tri-cyclic re-uptake inhibitors... and would in fact cause the tracers... Regardless that is initially cause by the Harmine... Take a fully visually active dose of Harma and see what I mean...

only three?
I thought I had a kajillion... :P

very true... there is such thing as "Water Poisoning" and you body is 70+% water....

ok to be fair, if you dont clean out the "poisons" before you take maoi's, you gonna really feel them with no inhibiters to break them down. jah know...

Om you told me you where taking SSRI's whilst you took Aya, and you learn tthat they where not compatible'

SSRI's an MAOI's don't mix'

Bliss'

Motumba'

saying DMT is not toxic is simply ridiculous. Serotonin is an endogenous neurotransmitter, in high amounts it will be fatal. DMT acts on the same receptors that serotonin does. When DMT binds to these receptors the synapse is flooded with serotonin. Repeated and frequent use of DMT could very well lead to permanent damage of these receptors. I am growing tired of this hippy-feel good nonsense about how because DMT is natural that it precludes any possibility of toxicity. Know your science and make informed decisions. Do not trust your brain to the rantings of someone who obviously knows nothing of neurochemistry.

om: "i dunno. when i drank ayahuasca i felt like i had been poisoned. Each time"

Everything which alters one's cognition in a bio-chemical sense may be deemed "toxic" to an extent. From Ritaline to LSD-25. The latter however in it's "normal" threshold dose is generally considered *virtually non toxic* due to the minute amounts required to reach said threshold state. But in excess, even LSD-25 will kill. Studies I read many years ago to do with DMT toxicity (yes, it is toxic in excess) pointed towards a low toxicity factor when used in moderation. 5-MeO DMT in particular was considered relatively safe in part due to the threshold dose being quite low as well as the body's apparent ability to de-aminate this simple structure rather quickly. Not to say that everything in minute doses is safe or non-toxic, of course.
According to the same study I mentioned, exogenous (external) administration of a moderate dose of 5-MeO DMT (8-12mg), without adding any MAOI, becomes practically undetectable (in blood) in a matter of minutes. This was one factor in the limited study's reserved conclusion that this compound was relatively safe in and of itself. Sorry, ain't got a link to this handy at the moment.

Repeat use of even the most benign entheogen can indeed alter one's brain function in a long term sense, for worse OR better. And that's without considering purely psychological aspects of any psychoactive substance use. But as far as any of them being actually poisonous to the body, psilocybin mushrooms for instance have a pretty hefty body load associated with them. This is why frequent use of this sacrament is inadvisable and many prefer to brew a tea with it in an effort to filter out some of it's arguably "nasty" (and not so useful) aspects. With aya, many consider the *poison* induced purge as an integral part of the experience. It's all relative really. As with many things in life, one has to carefully consider whether the benefits outweigh the risks. It is a personal choice.

We allow many toxins to enter our systems on a daily basis, whether we are aware of it, like it or not. Yes, some psychoactive compounds may be neurotoxic in and of themselves or set off a "toxic" response of sorts but are useful none the less in some sense, within moderation. Knowing what, why and how you're putting anything into your system key ;-)